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Duing concomitant tatmnt, duc dosags azathiopin and mcaptopuin t25-33% usual.

In tansing a patint om a uicosuic agnt tZYLOPIM (allopuinol) , th dos th uicosuic agnt should b gadually ducd ov a piod sval wks and th dos ZYLOPIM (allopuinol) gadually incasd tth quid dos ndd tmaintain a nomal sum uic acid lvl.

Tolbutamid’s convsion tinactiv mtabolits has bn shown tb catalyzd by xanthin oxidas om at liv. Th clinical signiicanc, i any, ths obsvations is unknown.

Allopuinol coms as a tablt ttak by mouth. It is usually takn onc twic a day, pably at a mal. Thlp you mmb ttak allopuinol, tak it aound th sam tim vy day. ollow th dictions on you psciption labl caully, and ask you doctphamacist txplain any pat you dnot undstand. Tak allopuinol xactly as dictd. Dnot tak mlss cheap Flomax it tak it motn than pscibd by you docto.

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allopurinol and its primary active metabolite, oxipurinol, are eliminated by the kidneys; therefore, changes in renal function have a profound effect on dosage.